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GC

What Is Gas Chromatography?

Gas Chromatography separates chemical compounds based on their volatility and interaction with a stationary phase inside a chromatography column. As compounds elute at different retention times, they are detected and recorded as a chromatogram.

GC is especially effective for analyzing low-molecular-weight organic compounds that cannot be easily identified by solid-state techniques.

What GC Measures

GC can be used to detect and quantify:

  • Volatile Organic Compounds (VOCs)

  • Residual solvents

  • Plasticizers and low-molecular additives

  • Processing aids and contaminants

  • Degradation products and by-products

  • Unknown volatile impurities

When combined with appropriate detectors or sample preparation methods, GC provides high sensitivity and excellent separation.

Why Use GC?

GC is chosen when volatile or semi-volatile components are suspected to play a role in performance or failure. It helps answer questions such as:

  • Are residual solvents present above acceptable levels?

  • What is causing unexpected odor or outgassing?

  • Are volatile impurities introduced during processing?

  • Do different batches or suppliers contain different volatile profiles?

  • Has degradation produced new volatile compounds?

Typical Application Scenarios

Impurity & Contamination Analysis

  • Identification of unexpected volatile contaminants

  • Investigation of odor-related complaints

  • Cleanliness and outgassing evaluation

Polymers, Plastics & Rubber

  • Residual monomer or solvent analysis

  • Additive and plasticizer screening

  • Comparison of formulations or suppliers

Pharmaceuticals & Medical Products

  • Residual solvent testing

  • Volatile impurity profiling

  • Stability and degradation studies

Failure Analysis & Troubleshooting

  • Investigation of discoloration, odor, or material degradation

  • Comparison of “good vs. failed” samples

  • Root-cause analysis involving volatile species

Quality Control & Supplier Qualification

  • Batch consistency verification

  • Incoming material screening

  • Process change validation

Sample Types

GC can be applied to:

  • solids (with appropriate extraction or headspace sampling)

  • liquids and solutions

  • polymers, resins, and coatings

  • adhesives, sealants, and consumer products

Sample preparation methods may include headspace analysis, solvent extraction, or thermal desorption, depending on the analytical objective.

What You Will Receive

Each GC project is delivered with a clear, structured report designed for engineering and quality decisions. A typical deliverable includes:

  • test objective and sample description

  • sample preparation and GC conditions

  • chromatograms with identified peaks

  • qualitative and/or quantitative results

  • comparison summaries (batch vs. batch, supplier vs. supplier)

  • interpretation of volatile components and their potential impact

  • recommendations for follow-up testing or corrective action

Why Choose Xinbodi for GC Analysis?

  • Experience with complex material matrices

  • Flexible sample preparation strategies tailored to your application

  • High sensitivity for trace-level volatile compounds

  • Clear interpretation linked to real-world performance

  • Support for R&D, QC, and failure investigations

  • Confidential handling of proprietary samples and data

FAQs

GC can separate unknowns, and tentative identification may be possible based on retention behavior. For definitive identification, GC is often combined with mass spectrometry (GC-MS).

GC analysis is destructive to the analyzed sample portion, but only small amounts are typically required.

Yes. GC can provide quantitative results when appropriate standards and calibration methods are used.

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